Human Adenovirus Type5 (dE1/E3) expressing Runt-related transcription factor 3 (RUNX3) under CMV promoter.
Description:
Runt-related transcription factor 3 (RUNX3), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Runt-related transcription factor 3
ACCN:
BC013362
Gene ID:
864
GI Number:
33878242
Fusion Tag:
V5 tag at C-terminal
Promoter:
CMV
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
RUNX3 gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
